Allergy & Clinical Immunology News

• Parental Stress and Depression Linked to Childhood Asthma Data from a national sample of Australian children showed worse asthma symptoms in the presence of family hardships, maternal depression, and other stressors.
  Medscape Medical News, November 30, 2023
• COVID Vax T-Cell Responses Help B-Cell–Deficient Patients The findings demonstrate how vaccine-induced T-cell responses could potentially reduce COVID-19 severity, the authors write.
  Medscape Medical News, November 29, 2023
• Tapinarof Effective for AD in Patients as Young as 2 years Tapinarof cream, 1%, an aryl hydrocarbon receptor agonist, was approved in 2022 for treating plaque psoriasis in adults.
  MDedge News, November 28, 2023
• Alert FDA Warns of Potentially Lethal Reaction to Seizure Meds Levetiracetam and clobazam can cause a rare but serious drug reaction with eosinophilia and systemic symptoms that can be life threatening if not diagnosed and treated quickly, the FDA warns.
  Medscape Medical News, November 28, 2023
• Global Measles Deaths Increased by 43% in 2022 The rise in measles outbreaks and deaths is not surprising, given the recent decline in vaccination rates, said an official of the US Centers for Disease Control and Prevention.
  Medscape Medical News, November 28, 2023
• Air in Remote First Nations Houses Tied to Respiratory Ills The air in First Nations houses in remote northwestern Ontario contains high concentrations of biocontaminants, mold, and fine particles that increase the risk of respiratory infections.
  Medscape Medical News, November 27, 2023
• Methotrexate Carries Higher Risk for Older CKD Patients Adverse event data showed an increased risk of myelosuppression, sepsis, pneumotoxic effects, or hepatotoxic effects.
  Medscape Medical News, November 27, 2023
• Parent Concerns a Factor When Treating Patients With AD For a parent whose child has an inflammatory skin disease, pigmentation changes, rather than inflammation, might be the reason that he or she brought the child to the clinician.
  MDedge News, November 23, 2023
• How Has the COVID-19 Pandemic Affected Sleep Quality? Researchers presented data about the relationship between sleep and outcomes such as response to vaccination and recovery from COVID-19.
  Medscape Medical News, November 22, 2023
• Risks Quantified in Medically Optimized Pregnancy With Lupus Patients who were not medically optimized for pregnancy were three times more likely to experience preterm birth and preeclampsia.
  Medscape Medical News, November 21, 2023
• AHA 2023 Alternative Antirejection Regimen in Pediatric Heart Transplant Results of the head-to-head TEAMMATE trial show the combination of everolimus and low-dose tacrolimus can be considered an alternative to MMF plus tacrolimus in pediatric heart transplant.
  MDedge News, November 21, 2023
• Why Intense Exercise May Lead to a Cold Inactivity has emerged as a risk factor for respiratory infections but too much physical activity could also increase susceptibility.
  Medscape Medical News, November 21, 2023
• ACR 2023 Novel Blood Test Can Detect Rheumatoid Arthritis An experimental assay detects epigenetic features within the unique patterns and sizes of cell-free DNA found in blood, but is it better than clinical diagnostics?
  MDedge News, November 20, 2023
• Lebrikizumab Gets the Nod in the EU for Atopic Dermatitis Lebrikizumab, an interleukin-13 inhibitor, is not yet approved in the United States.
  MDedge News, November 20, 2023
• Use the Stool! Fecal Transplants Help Kids With C Diff The American Academy of Pediatrics endorsed fecal transplants to eliminate a particular infection in children and called for more research about other uses.
  Medscape Medical News, November 20, 2023
• Before Signing an Offer Letter: Read This You just received an offer letter, but should you sign it right away? How legally binding is it? Is it the same as a contract? Experts weigh in.
  Medscape Medical News, November 17, 2023
• New Consensus Guide on Rare Drug Hypersensitivity Reaction Experts provided parameters to help clinicians, but they acknowledged the limited evidence base for drug reaction with eosinophilia and systemic symptoms.
  Medscape Medical News, November 17, 2023
• ACR 2023 Split-Dose Methotrexate Speeds RA Response Over Single Dose Compared with a single dose, more patients in the split-dose group had improved disease activity at 16 weeks, and fewer needed additional DMARDs, but the effect was not found at 24 weeks.
  Medscape Medical News, November 16, 2023
• ChatGPT Gives Incorrect Answers About EoE ChatGPT provides a mix of accurate and inaccurate information to common questions about eosinophilic esophagitis, according to a new study.
  Medscape Medical News, November 16, 2023
• Isothiazolinone Allergy Common, Often to Multiple Allergens Many people in North America appear to be allergic to one or more of a family of preservatives used in personal care products and household cleaners implicated in the global spread of allergic contact dermatitis.
  Medscape Medical News, November 15, 2023
• ACAAI 2023 Saltwater Gargling May Help Avoid COVID Hospitalization Gargling and nasal rinsing were associated with a significant reduction in the hospitalization rate for people with COVID; if confirmed, the finding could be helpful in low-resource settings, says researcher.
  Medscape Medical News, November 14, 2023
• Should Physicians Go to Work When Sick? Although most doctors believe it's best to stay home if they're ill, today's healthcare system makes the answer much more complicated.
  Medscape Medical News, November 13, 2023
• CAR-T Therapy for NHL Treats Concurrent Rheumatic Disease CAR–T cell therapy for non-Hodgkin lymphoma appeared as safe and effective in patients with rheumatic autoimmune disease as in those without and also improved control of the underlying autoimmunity.
  Medscape Medical News, August 24, 2023
• First Guidelines Developed for Childhood EGIDs Beyond EoE Limited existing literature spurred the development of a consensus document to guide the diagnosis and treatment of rare eosinophilic diseases.
  Medscape Medical News, August 23, 2023
• UK's First Living Donor Uterus Transplant a Success After 25 years' preclinical research, a British surgical team reported the UK's first living donor uterus transplant, with both donor and recipient doing well 10 weeks post-operatively.
  Medscape News UK, August 23, 2023
• As MOC Debate Heats Up, Cardiology Societies Weigh In The MOC process is once again under attack by cardiologists and other specialty physicians. A petition aiming to end the requirements has garnered more than 17,000 and counting signatures.
  Medscape Medical News, August 22, 2023
• Patient Identified Who Battled COVID for 505 Days An immunocompromised patient was identified with persistent SARS-CoV-2 infection lasting 505 days, the longest known to date.
  Medscape News UK, April 22, 2022