Pharmacists News

• Sublingual Film Well-Tolerated for Parkinson 'Off' Episodes Even without the use of antiemetic drugs, apomorphine sublingual film was well tolerated to treat Parkinson 'off' episodes, the most common adverse event being mild nausea, a study has shown.
  Medscape Medical News, September 19, 2021
• ESMO 2021 New Standard of Care in Cervical Cancer The combination resulted in significant improvements in both progression-free and overall survival compared with chemotherapy (with or without bevacizumab) alone.
  Medscape Medical News, September 19, 2021
• ESMO 2021 BrighTNess Follow-Up Data Shed Light on TNBC Therapy Patients with triple negative breast cancer had improved event-free survival when carboplatin (but not the PARP inhibitor veliparib) was added to standard neoadjuvant chemotherapy.
  Medscape Medical News, September 18, 2021
• ESOC 2021 Ticagrelor of Net Clinical Benefit aAfter Stroke, TIA: THALES A new analysis of data from the THALES trial separates out the reduction in ischemic events from the increase in bleeding events and shows the benefit outweighs the risk in a ratio of four-to-one.
  Medscape Medical News, September 17, 2021
• Alert European Agency Recommends Two New Adalimumab Biosimilars The Committee for Medicinal Products for Human Use gave a positive opinion for the approval of Hukyndra and Libmyris, each of which will have 15 indications.
  International Approvals, September 17, 2021
• Alert FDA Panel Backs Pfizer's COVID Booster for 65 and Older, High Risk Pfizer's application for a third dose of its mRNA COVID-19 vaccine was earlier rejected by the panel for those 16 and over.
  Medscape Medical News, September 17, 2021
• EURETINA 2021 Gene Therapy Research Accelerates for Retinal Diseases Patients who have rare retinal diseases — as well as those with more common ones — may benefit from a surge in gene therapy research.
  Medscape Medical News, September 17, 2021
• Alert EMA Endorses Injectable Malaria Drug Artesunate The drug, which was approved by the FDA last year, is an initial treatment of severe malaria in adults and children.
  International Approvals, September 17, 2021
• ESMO 2021 Nivo/Ipi Combo Now 'Standard of Care' in Mesothelioma Patients with malignant pleural mesothelioma have a marked and sustained overall survival benefit with nivolumab and ipilimumab vs chemotherapy, even if they discontinue treatment.
  Medscape Medical News, September 17, 2021
• Alert Flurry of Cancer Drug Endorsements From EU Panel The European Medicines Agency panel recommended for approval three new cancer drugs and additional indications for two other already marketed immunotherapies.
  International Approvals, September 17, 2021
• WCLC 2021 Improved Survival in Patients With NSCLC and Brain Metastases About a third of the patients with NSCLC and brain metastases treated with atezolizumab in combination with chemotherapy had overall survival improved to 2 years.
  Medscape Medical News, September 17, 2021
• WCLC 2021 'Urgent' Need to Understand Immunotherapy De-escalation in NSCLC The strong and durable response to immunotherapy in some patients suggests treatment could be reduced or withdrawn, but questions surround which patients will be ideal candidates, an expert argues.
  Medscape Medical News, September 17, 2021
• EMA Panel Backs Diroximel Fumarate (Vumerity) for MS Diroximel fumarate is similar to dimethyl fumarate (Tecfidera) in efficacy but has a unique chemical structure that may induce less irritation to the gastrointestinal tract.
  Medscape Medical News, September 17, 2021
• HPV Vaccine Safety Concerns Up 80% From 2015 to 2018 But adverse events after HPV vaccination actually decreased during the same period, researchers found.
  Medscape Medical News, September 17, 2021
• HFSA 2021 Texts Boost Activity, QOL in Patients With HF and Diabetes A 3-month lifestyle intervention using a step counter and text messages to encourage activity and medication adherence led to improved quality of life in a randomized study in HF and diabetes.
  Medscape Medical News, September 17, 2021
• Boost Vitamin D in Blacks Living at High Latitudes, Study Indicates Those of African-Caribbean descent who reside at higher latitude, lower UVB-exposure regions show vitamin D deficiencies. Supplementation can help.
  Medscape Medical News, September 17, 2021
• Pegcetacoplan Shows Mixed Results for Geographic Atrophy Two phase 3 trials yielded different results for pegcetacoplan as a treatment for geographic atrophy.
  Medscape Medical News, September 17, 2021
• Baylor Gets Restraining Order Against COVID Vaccine Skeptic Doc The health system is seeking $1 million in damages against internist and cardiologist Peter McCullough, MD, for allegedly continuing to claim an affiliation after signing a separation agreement.
  Medscape Medical News, September 16, 2021
• Trinidad Health Minister Calls Nicki Minaj's COVID Vax Claim False Terrence Deyalsingh, the health minister for Trinidad and Tobago, said her story was inaccurate and called it a waste of time.
  WebMD Health News, September 16, 2021
• FDA Analysis Chills the Rush to Approve Boosters An FDA report released this week has added doubt to the outcome of an advisory committee meeting on Friday to consider a third booster dose for the Pfizer COVID vaccines.
  Medscape Medical News, September 16, 2021