Nephrology News

• Troponin, Echo a Prognostic Power Combo in COVID-19 Mortality climbed sixfold in patients admitted with SARS-CoV-2 infection with positive troponins who also had major abnormalities by selectively performed echocardiography in a registry study.
  Medscape Medical News, October 27, 2020
• Study Supports Citrate Over Heparin Anticoagulation for Continuous Dialysis A large randomized controlled trial supports the use of regional citrate over heparin anticoagulation to help prevent blood clot formation at the filter in patients receiving continuous dialysis therapies.
  Reuters Health Information, October 26, 2020
• KidneyWeek 2020 CV Benefit of Eicosapentaenoic Acid Seen at All eGFR Levels Daily icosapent ethyl safely reduced fatal and nonfatal ischemic events in patients with reduced kidney function in an extension of the REDUCE-IT trial.
  Medscape Medical News, October 27, 2020
• IDWeek 2020 TDF Preferred in PrEP for Blacks and Women, Studies Indicate "I think when we're comparing these two drugs overall, we have a clear benefit/risk, and we need to take both of these potential toxicities seriously," said a pharmacology researcher at ID Week2020.
  Medscape Medical News, October 27, 2020
• Higher Serum Omega-3 Tied to Better Outcome After STEMI Regular consumption of marine-derived and vegetable-derived omega-3s was associated with improved prognosis after STEMI, observational data show.
  Medscape Medical News, October 27, 2020
• COVID-19: Thromboembolic Events High Despite Prophylaxis However, new US data show the rates of thromboembolism are not as high as reported in earlier studies from Asia and appear similar to what would be expected in other very sick patients in ICU.
  Medscape Medical News, October 26, 2020
• KidneyWeek 2020 Cardiovascular Safety Results for Anemia Drug Disappoint Vadadustat did not meet the noninferiority criteria for cardiovascular safety in the PRO2TECT studies that compared the HIF inhibitor with an erythropoiesis-stimulating agent.
  Medscape Medical News, October 26, 2020
• Vosoritide Ups Height in Achondroplasia in Year-Long Phase 3 Study A phase 3 study of the investigational drug vosoritide establishes it as the first precision treatment for children with achondroplasia, the most common type of dwarfism, say researchers.
  Medscape Medical News, October 26, 2020
• KidneyWeek 2020 Novel Drug Slows Progression of Diabetic Kidney Disease Finerenone, a selective, nonsteroidal mineralocorticoid receptor antagonist, significantly reduced both renal and cardiovascular events, with good tolerability, in the FIDELIO-DKD trial.
  Medscape Medical News, October 23, 2020
• Decision on Race Multiplier in CKD in Blacks 'Has Real Consequences' Dropping the eGFR multiplier for African Americans produced a 33% hike in those assigned to a more severe stage of chronic kidney disease. But whether or not to keep the adjustment remains unclear, say experts.
  Medscape Medical News, October 23, 2020
• DVT Screening, Early Treatment, Prevent PE in Necrotizing Pancreatitis Ultrasound screening enabled identification and early treatment of extremity deep vein thrombosis (DVT), thereby preventing symptomatic pulmonary embolism (PE) in a single center trial.
  Reuters Health Information, October 21, 2020
• TCT 2020 TCT Intravascular Lithotripsy Hailed for Coronary Calcification Intravascular lithotripsy proved highly effective, safe, and user friendly as an adjunct to stenting for severely calcified coronary lesions at 30 days of follow-up in the pivotal Disrupt CAD III study.
  Medscape Medical News, October 19, 2020
• Fellowship Training and COVID: Obstacles and Opportunities The pandemic is an opportunity to assess clinical competency vs metrics, with the pivot from hands-on training to virtual solutions. But most agree that there is no replacement for human connection.
  Medscape Medical News, October 19, 2020
• It's Complex: Rise in Diabetes Drug Costs in US Is Multifactorial More users, higher insulin cost-per-user, and greater use of newer noninsulin medicines are key, but other factors also play a role.
  Medscape Medical News, October 16, 2020
• Has Trump’s Case Affected Your Impression of COVID-19? Just over a week after President Trump announced he had tested positive for SARS-CoV-2 infection, the White House doctor said the president was 'no longer considered a transmission risk to others.'
  Medscape Reader Polls, October 16, 2020
• Alert FDA Issues New NSAIDs Warning for Second Half of Pregnancy The agency links potential for low amniotic fluid and kidney issues in unborn children with over-the-counter and prescription NSAIDs, with the exception of 81 mg aspirin.
  News Alerts, October 15, 2020
• COVID Jump-Starts 'Health Passport' App The remote diagnostic test and vaccine data storage platform could be used to verify who is COVID-free in workplaces, schools, and venues.
  Medscape Medical News, October 15, 2020
• Doc Reminders, Patient Payments to Increase Statins? Electronic 'nudges' may boost physician prescribing of statins; paying patients to take the medication helped with adherence but ultimately didn't significantly reduce lipid levels, in new studies.
  Medscape Medical News, October 15, 2020
• COVID-19 Antibody Response Not Reduced With Diabetes Findings provide 'cautious optimism' that a COVID-19 vaccine would be expected to work as well in people with diabetes as those without.
  Medscape Medical News, October 15, 2020
• EAS 2020 Inclisiran Effectively Lowers LDL Across High-risk Settings Patients with heterozygous FH, regardless of phenotype, and those at high risk for a first cardiovascular event had huge LDL cholesterol reductions with inclisiran, the latest ORION data show.
  Medscape Medical News, October 15, 2020