Center of Excellence: Migraine: News & Perspective

• AAN 2021 Migraineurs Not Taking Advantage of an 'Effective Prophylactic' Getting the recommended amount of exercise can help reduce migraine days and mi-graine triggers such as stress, depression, and sleep problems, new research suggests.
  Medscape Medical News, March 02, 2021
• Alert FDA Clears Neuromodulation Device for Acute Migraine Pain Relivion is an adjustable headset that delivers modulated pulses of electric current through adaptive output channels around the head to six branches of the occipital and trigeminal nerves.
  FDA Approvals, March 02, 2021
• Nystagmus From Living in the Dark Cured With Light Exposure A new case report of so-called miner's nystagmus demonstrates the remarkable plasticity of the brain, the authors say, and suggests that historical reports of this condition by miners were genuine.
  Medscape Medical News, February 24, 2021
• Opioid Overuse in Migraineurs Linked to More Severe Disability Among patients with migraine who use prescription medications, the increasing use of prescription opioids is associated with chronic migraine, anxiety, and depression, according to a new analysis.
  Medscape Medical News, February 11, 2021
• PFO Closure Reduces Migraine: New Meta-Analysis Pooled results from the PRIMA and PREMIUM randomized trials show significant benefits in several key endpoints, prompting the authors to conclude the approach warrants re-evaluation.
  Medscape Medical News, February 08, 2021
• CGRP May Offer Both Migraine Treatment and Prevention Oral rimegepant, the first calcitonin gene-related peptide (CGRP) receptor antagonist approved for the acute treatment of migraine, was superior to placebo in preventing migraine in a phase 2/3 trial.
  Medscape Medical News, December 22, 2020
• 'Dramatic Impact' of Mindfulness on Migraine Study shows that mindfulness-based stress reduction improves disability, depression, and quality of life among migraine sufferers but doesn't reduce migraine frequency compared to headache education.
  Medscape Medical News, December 17, 2020
• HIT-6 Helps Track 'Meaningful Change' in Chronic Migraine A more than 6-point improvement in HIT-6 total score and a 1-2 category improvement in item-specific scores associated with meaningful change in an individual with chronic migraine, research suggests.
  Medscape Medical News, October 16, 2020
• Migraine Nerve Stimulation Device Now Available Over-the-Counter Cefaly Dual is a dual-purpose, external trigeminal nerve stimulation device to treat and prevent acute migraine headache in adults.
  Medscape Medical News, October 13, 2020
• No Migraine 'Rebound' Stopping Clopidogrel After ASD Closure Some concern has been raised that stopping DAPT too soon may increase migraine risk, but a new study offers reassuring findings.
  Medscape Medical News, October 05, 2020
• Choroid Plexuses May Play a Role in Migraine Levels of soluble vascular cell adhesion molecule 1 in cerebrospinal fluid could serve as a biomarker of the mechanisms underlying migraine.
  Medscape Medical News, August 24, 2020
• Multiple Traits More Common in Difficult-to-Treat Migraine Patients with difficult-to-treat migraines are 'more medically and psychosocially complex,' according to a new study.
  Medscape Medical News, August 14, 2020
• Botulinum Toxin Linked to Antidepressant Effects A study found significant associations between use of of botulinum toxin and antidepressant effects.
  Medscape Medical News, August 12, 2020
• Positive Phase 3 Topline Results for Migraine Prevention Drug Topline results from the phase 3 ADVANCE trial show that all three doses evaluated of the novel CGRP medication atogepant met the primary endpoint of reduced monthly migraine days.
  Medscape Medical News, July 30, 2020
• Visualization Tool Aids Migraine Management A new visualization tool helps patients and clinicians communication about risk factors for progression from episodic to chronic migraines.
  Medscape Medical News, July 01, 2020
• Migraine Often a Deciding Factor in Pregnancy Planning Migraine can significantly affect a woman's decision to become pregnant, especially those who are younger and have menstrual or chronic migraine, new research suggests.
  Medscape Medical News, July 01, 2020
• Headache Day 'Threshold' for Chronic Migraine Called Into Question Results of a large analysis call into question the existing threshold of 15 migraine headache days per month to distinguish low- and high-frequency migraine.
  Medscape Medical News, June 22, 2020
• NSAID/Triptan Combo Improves Treatment-Resistant Migraine A combination of rizatriptan and the NSAID meloxicam formulated to improve oral absorption led to better pain control than did rizatriptan alone in a phase 3 clinical trial.
  Medscape Medical News, June 19, 2020
• Intranasal DHE Promising in Migraine An intranasal form of dihydroergotamine is safe and effective for the treatment of migraine, according to results from a phase 3 clinical trial.
  Medscape Medical News, June 19, 2020
• CGRPs in Real World: Similar Efficacy, More AEs In a study of the use of calcitonin gene-related peptide receptor (CGRP) monoclonal antibodies for the treatment of migraine, rates of adverse events were higher than other studies have found.
  Medscape Medical News, June 19, 2020