Gastroenterology News

• Alert EMA Issues Positive Opinion on the Safety of Filgotinib The EMA has issued a positive opinion of the type II variation application of the JAK1 inhibitor filgotinib, based on testicular function safety data from two phase 2 clinical trials.
  International Approvals, October 04, 2022
• Risk-Adapted Screening Strategy Could Reduce Colonoscopy Use In countries with limited healthcare resources, risk-adapted screening strategies could be more cost-effective and accessible, according to study authors.
  MDedge News, October 04, 2022
• Bariatric Surgery May Up Risk for Epilepsy Bariatric surgery can raise the risk of developing epilepsy, new research suggests. However, experts note the mechanisms for this association are unclear.
  Medscape Medical News, October 04, 2022
• Breakthrough Studies Support New Boosters in Immunosuppressed The findings of two studies underscore the importance of booster vaccine doses in those with immune-mediated inflammatory diseases who are taking immunosuppressants.
  Medscape Medical News, October 04, 2022
• Will Real Meat Grown in a Lab Be Good for Us? Produced from a single animal cell, cultivated meat is hailed as a slaughter-free way to feed more people without the environmental harm — and it can be made healthier. But is it too good to be true?
  WebMD Health News, October 04, 2022
• New Liver Stiffness Thresholds Refine NASH Risk Stratification These new thresholds are based on high-quality prospective data drawn from four randomized controlled trials.
  MDedge News, October 03, 2022
• Air Pollution Linked to Increased IBS Incidence This study is the first to comprehensively investigate whether these associations might exist at all, according to the authors.
  MDedge News, October 03, 2022
• Intercept's NASH Drug Fails Late-Stage Trial, Shares Tumble Intercept Pharmaceuticals said on Friday its treatment for patients with advanced liver scarring due to non-alcoholic steatohepatitis failed to meet the main goal of a late-stage study, sending its shares down as much as 21%.
  Reuters Health Information, September 30, 2022
• Distensibility Index: A 'Game Changer' in Pediatric EoE? Measuring esophageal distensibility can help define the severity of early scarring in the esophagus of children with eosinophilic esophagitis and guide care.
  Medscape Medical News, October 03, 2022
• Will AI Affect the Burden of Surveillance After Polyp Removal? AI-assisted colonoscopy may increase the proportion of US patients requiring intensive postpolypectomy colonoscopy surveillance by roughly 35%.
  Medscape Medical News, October 03, 2022
• Alert FDA Approves Futibatinib for Certain Biliary Tract Cancers The indication is for use in adult patients with previously treated intrahepatic cholangiocarcinoma harboring fibroblast growth factor receptor 2 (FGFR2) gene fusions or other rearrangements.
  FDA Approvals, October 03, 2022
• Balanced Fat Intake Links With Less Type 2 Diabetes Chinese adults whose diet balanced their animal- and vegetable-fat intake had a significantly lower incidence of type 2 diabetes compared with those with a less balanced intake.
  First Look, October 03, 2022
• IBD Appears More Prevalent in Men Who Have Sex With Men There are several hypotheses around what might account for this differing prevalence, but they require additional studies to confirm, according to researchers.
  Medscape Medical News, September 30, 2022
• EASD 2022 Strong Link Found Between Enterovirus and Type 1 Diabetes Relationship is particularly high within 1 month of type 1 diabetes onset, suggesting potential preventive role for vaccination or antivirals.
  Medscape Medical News, September 30, 2022
• EASD 2022 Liver Fat Lowered by Ezetimibe-Statin Combination A significant 5.8% decrease in hepatic steatosis was seen after 24 weeks’ treatment with ezetimibe and rosuvastatin comparing baseline with end of treatment values.
  MDedge News, September 30, 2022
• Alert FDA Clears Nexpowder Endoscopic Hemostasis System Nexpowder provides improved visibility and control for treating nonvariceal upper GI bleeding, according to the company's news release.
  FDA Approvals, September 29, 2022
• Could Your Patients Benefit? New Trials in Noncolorectal GI Cancer Several studies in noncolorectal GI cancers have started enrolling recently. Here's the 411 on those trials.
  Medscape Medical News, September 29, 2022
• Physiatrist Group Issues First Guidelines for Long COVID in Kids The American Academy of Physical Medicine & Rehabilitation issued two statements on how to assess and treat long COVID in kids, and to do the same for long COVID-related autonomic nervous system problems.
  Medscape Medical News, September 29, 2022
• Food Insecurity a Growing Problem for Many With CVD The number of Americans with cardiovascular disease who have limited or uncertain access to food has more than doubled over the last 20 years, a review of NHANES data show.
  Medscape Medical News, September 29, 2022
• Novel Tool Aims to Simplify Crohn's Disease Assessment A simplified method of scoring Crohn's disease activity and severity can accurately and reliably assess patients, suggests a retrospective analysis.
  Medscape Medical News, September 29, 2022