Figure 1. Axial MR images obtained in a 14-year-old boy with NF1. Left: Image demonstrating brainstem signal change indicative of hamartomatous elements within the lesion. Right: A higher axial image with contrast demonstrating large left parietal hemorrhagic lesion that proved intraoperatively to be a malignant glioma.
Figure 2. Axial CT scan revealing left parietal mass lesion in a 12-year-old boy who had undergone 5000-rad radiotherapy at age 4 years for a low-grade optic chiasmatic glioma. At age 12 years, the lesion proved to be a malignant glioma and arose in the prior radiation therapy field.
Figure 3. Axial MR image obtained in a 14-year-old girl with a left occipital high-grade glioma. The lesion enhanced inhomogeneously and was associated with mass effect and some edema.
Figure 4. Intraoperative photograph of high-grade glioma at the cortical surface. Note the variegated appearance of the tumor at the time of surgery.