What is the role of surgery in the treatment of pediatric neuroblastoma?

Updated: Oct 09, 2017
  • Author: Norman J Lacayo, MD; Chief Editor: Max J Coppes, MD, PhD, MBA  more...
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Answer

Surgical resection plays an important role in the treatment of patients with neuroblastoma. For patients with localized disease, surgical resection is curative. For patients with regional or metastatic disease, surgery to establish a diagnosis and obtain adequate samples for biologic studies is essential. Typically, second-look surgery postchemotherapy is used to attempt a complete resection. The emphasis in the second-look procedure is as complete a debulking as possible without sacrificing major organ function. Patients with residual disease postchemotherapy and surgery may benefit from the use of radiotherapy.


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