Which medications in the drug class Corticosteroids are used in the treatment of Pediatric Non-Hodgkin Lymphoma?

Updated: Jun 14, 2018
  • Author: J Martin Johnston, MD; Chief Editor: Max J Coppes, MD, PhD, MBA  more...
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Answer

Corticosteroids

Corticosteroids elicit anti-inflammatory properties and cause profound and varied metabolic effects. They modify the body's immune response to diverse stimuli.

Methylprednisolone (Medrol, A-Methapred, Solu-Medrol)

The mechanism of cytotoxicity for methylprednisolone is unknown, but it is apparently mediated by glucocorticoid receptors.

Dexamethasone (Baycadron)

The mechanism of cytotoxicity for dexamethasone is unknown, but it is apparently mediated by glucocorticoid receptors. The drug's action is apparently enhanced by CNS penetration (relative to prednisone).


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