Which medications in the drug class Progestins are used in the treatment of Pediatric Non-Hodgkin Lymphoma?

Updated: Jun 14, 2018
  • Author: J Martin Johnston, MD; Chief Editor: Max J Coppes, MD, PhD, MBA  more...
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Answer

Progestins

These agents may induce endometrial thinning by inhibiting the secretion of pituitary gonadotropins.

Norethindrone acetate (Aygestin, Camila, Errin)

Norethindrone is a common progestin used in many of the oral contraceptive pills currently available. Progestins stop endometrial cell proliferation, allowing organized sloughing of cells after withdrawal. These agents typically do not stop acute bleeding episode, but they produce normal bleeding episodes following withdrawal.

Medroxyprogesterone (Depo-Provera, Provera)

Progestins stop endometrial cell proliferation, allowing organized sloughing of cells after withdrawal. These agents typically do not stop acute bleeding episode, but they produce normal bleeding episodes following withdrawal.

Medroxyprogesterone is a common progestin available in both an oral and an intramuscular depo form. The efficacy and adverse effects of this drug are similar to those of norethindrone.


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