How is the risk of respiratory arrest mitigated when performing diagnostic procedures for suspected pediatric non-Hodgkin lymphoma (NHL)?

Updated: Jun 14, 2018
  • Author: J Martin Johnston, MD; Chief Editor: Max J Coppes, MD, PhD, MBA  more...
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Answer

Mediastinal or cervical lymphomas may cause airway compromise. The potential for respiratory arrest must be recognized, particularly if sedation or general anesthesia is administered for a diagnostic procedure.

Consider (1) administering local anesthesia alone for lymph node biopsy; (2) establishing a diagnosis with pleural fluid, peritoneal fluid, or bone marrow aspiration; and (3) performing local irradiation to stabilize the airway before obtaining a diagnostic specimen from a site outside the radiation field.


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