Which clinical history findings are characteristic of pediatric non-Hodgkin lymphoma (NHL)?

Updated: Jun 14, 2018
  • Author: J Martin Johnston, MD; Chief Editor: Max J Coppes, MD, PhD, MBA  more...
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The presentation of patients with non-Hodgkin lymphoma is acute or subacute, in contrast to the indolent course that characterizes most lymphomas in adults.

The duration of symptoms before diagnosis is generally 1 month or less, with specific complaints varying according to the predominant sites of involvement.

Bone marrow involvement in non-Hodgkin lymphoma may cause generalized or migratory bone pain, but clinically significant cytopenias are uncommon, with their presence suggesting a diagnosis of acute leukemia.

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