What is the role of cytogenetics in the workup of pediatric acute myelocytic leukemia (AML)?

Updated: Sep 12, 2017
  • Author: Mark E Weinblatt, MD; Chief Editor: Jennifer Reikes Willert, MD  more...
  • Print
Answer

Analysis of the chromosome changes in the leukemic cell is often performed to confirm the diagnosis and for prognostic purposes. If patients have the 9;22 translocation, this would indicate an underlying chronic myelogenous leukemia that would necessitate treatment with tyrosine kinase inhibitors and possibly stem cell transplantation. FLT3 would likewise be an important prognostic marker.


Did this answer your question?
Additional feedback? (Optional)
Thank you for your feedback!