Which medications are used in the treatment of pediatric acute myelocytic leukemia (AML)?

Updated: Sep 12, 2017
  • Author: Mark E Weinblatt, MD; Chief Editor: Jennifer Reikes Willert, MD  more...
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Answer

Pharmacotherapy used in managing AML includes the following medications:

  • Chemotherapeutic drugs: Cytarabine (cytosine arabinoside), fludarabine, daunorubicin (daunomycin), etoposide, amsacrine, 6-thioguanine, cyclophosphamide, mitoxantrone, tretinoin, arsenic trioxide, L-asparaginase, gemtuzumab ozogamicin, sorafenib, clofarabine

  • Antiemetic drugs: Ondansetron, granisetron, palonosetron, lorazepam, aprepitant, dexamethasone

  • Prophylactic broad-spectrum antimicrobials: Trimethoprim-sulfamethoxazole, penicillin

  • Prophylactic antifungals: Fluconazole, nystatin, voriconazole, caspofungin, micafungin

  • Tumor lysis: Allopurinol, rasburicase


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