What are the signs and symptoms of pediatric acute myelocytic leukemia (AML) due to a deficiency of normally functioning cells?

Updated: Sep 12, 2017
  • Author: Mark E Weinblatt, MD; Chief Editor: Jennifer Reikes Willert, MD  more...
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Answer

Signs and symptoms of pediatric acute myelocytic leukemia (AML) can be divided into the following: (1) those caused by a deficiency of normally functioning cells, (2) those due to the proliferation and infiltration of the abnormal leukemic cell population, and (3) constitutional symptoms.

Symptoms due to a deficiency of normally functioning cells include the following:

  • Cytopenias: Can result from a deficiency of normally functioning cells

  • Anemia: Characterized by pallor, fatigue, tachycardia, and headache

  • Hemorrhage: Most commonly, easy bruising, petechiae, epistaxis, gingival bleeding

  • Fever: Should initially always be attributed to infection


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