What are the NANETS recommendations for treatment of advanced pheochromocytoma and paraganglioma?

Updated: Feb 12, 2019
  • Author: Cameron K Tebbi, MD; Chief Editor: Max J Coppes, MD, PhD, MBA  more...
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Answer

The 2010 NANETS recommendations for treatment of advanced disease include the following [118] :

  • Surgical debulking to release tumor pressure on surrounding tissues or to decrease tumor mass

  • In select patients, radiofrequency ablation or cryoablation are options

  • Chemotherapy is preferred in patients with negative metaiodobenzylguanidine (MIBG) scintigraphy and in those with rapidly progressing tumors

  • External-beam irradiation of bone metastases or radiofrequency and cryoablation in selected cases only


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