What are the less common symptoms of carcinoid tumors?

Updated: Feb 12, 2019
  • Author: Cameron K Tebbi, MD; Chief Editor: Max J Coppes, MD, PhD, MBA  more...
  • Print


  • Relatively uncommon complaints include joint pain, arthritis, lacrimation, confusion and changes in mental status, ophthalmologic findings associated with flushing or secondary to vascular occlusion, retroperitoneal fibrosis, obstruction of ureter, intra-abdominal fibrosis, Cushing syndrome and male sexual dysfunction.

  • Skin hyperkeratosis and pigmentation and arthritis are also relatively uncommon.

  • Carcinoid tumors have occurred in association with other familial or genetic disorders, such as multiple endocrine neoplasia type 1 (MEN 1) [54] and Peutz-Jeghers syndrome.

  • Multicentric tumor involving more than one organ (eg, larynx and thyroid) has been reported. [55, 56]

  • A second primary tumor in association GI carcinoids can occur. A case of hepatocellular carcinoma post diagnosis of carcinoid tumor has been reported. [57] These secondary tumors tend to be aggressive. In all cases of carcinoid tumor, care should be given to evaluate and follow patients for possible second malignancies.

Did this answer your question?
Additional feedback? (Optional)
Thank you for your feedback!