What are the racial predilections of chronic kidney disease (CKD) in children?

Updated: Jul 21, 2020
  • Author: Sanjeev Gulati, MD, MBBS, DNB(Peds), DM, DNB(Neph), FIPN(Australia), FICN, FRCPC(Canada); Chief Editor: Craig B Langman, MD  more...
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Answer

ESRD rates in Black individuals are 2.7 times higher than in White individuals, which may be due to genetic susceptibility; other factors may include socioeconomic problems and limited access to medical care. Such factors may result in the delivery of excessive numbers of low birth weight (LBW) babies, partially accounting for the observed increased incidence of ESRD, because chronic kidney disease is more common with increasing prematurity and survivorship.

Choi et al found that rates of ESRD among Black patients exceeded those among White patients at all levels of baseline eGFR. [10] Similarly, mortality rates among Black patients were equal to or higher than those among White patients at all levels of eGFR. Risk of ESRD among Black patients was highest at an eGFR of 45-59 mL/min/1.73 m2, as was the risk of mortality. [1]


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