Which findings from serial urine samples suggest Henoch-Schönlein purpura (IgA vasculitis)?

Updated: Jan 08, 2021
  • Author: Rajendra Bhimma, MBChB, MD, PhD, DCH (SA), FCP(Paeds)(SA), MMed(Natal); Chief Editor: Craig B Langman, MD  more...
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Answer

If serial urine samples are obtained in patients with IgAV, microscopic hematuria is usually found; it is probably present in 100% of cases. However, frank nephritis appears in only 20-30% of unselected children. The entire clinical spectrum of glomerulonephritis may occur in IgAV. The most common kidney manifestations are hematuria with mild-to-moderate proteinuria.


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