What are vascular and hematologic findings suggestive of Henoch-Schönlein purpura (IgA vasculitis)?

Updated: Jan 08, 2021
  • Author: Rajendra Bhimma, MBChB, MD, PhD, DCH (SA), FCP(Paeds)(SA), MMed(Natal); Chief Editor: Craig B Langman, MD  more...
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Vasculitis involving the myocardium may occur. Vasculitis may also involve the lungs, resulting in pulmonary hemorrhage or severe bilateral pulmonary hemorrhage, and it may cause stenosing ureteritis, priapism, penile edema, or orchitis. Ha and Lee reported that neurologic symptoms, localized edema, and high serum C3 levels were significantly correlated with scrotal involvement in male patients with IgAV. [74] Vasculitis involving the CNS and intracranial hemorrhage have been reported.

Bilateral subperiosteal orbital hematomas have been noted. Adrenal hematomas have occurred. In rare patients, acute pancreatitis is the sole presenting feature of IgAV. [84, 85, 4] A case involving cystic changes of the ovaries and IgAV has been reported. [41]

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