What is the recurrence rate for Henoch-Schönlein purpura (IgA vasculitis)?

Updated: Jan 08, 2021
  • Author: Rajendra Bhimma, MBChB, MD, PhD, DCH (SA), FCP(Paeds)(SA), MMed(Natal); Chief Editor: Craig B Langman, MD  more...
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Disease recurrence occurs throughout weeks to months in adults and children. In a large pediatric study by Allen et al, children older than 2 years had a recurrence rate of 50%, whereas those younger than 2 years had a recurrence rate of less than 25%. [79]

Prais et al studied 267 children (56.7% males) who were hospitalized secondary to IgAV  of whom 7 (2.7%) had IgAV that resulted in hospitalization at least twice. [80] No specific risk factor for recurrence was determined. The mean age for the first recurrence in that subgroup was 3.67 years (range, 10 months to 7.4 years), and that for the second was 5.03 years (range, 2.2-10 years), with a mean lag time of 13.5 ± 2.8 months (range, 2-26 months). The duration of the recurrence was 9-30 days. Resolution took more than 2 weeks in 72% of patients.

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