What are GI symptoms of Henoch-Schönlein purpura (IgA vasculitis)?

Updated: Jan 08, 2021
  • Author: Rajendra Bhimma, MBChB, MD, PhD, DCH (SA), FCP(Paeds)(SA), MMed(Natal); Chief Editor: Craig B Langman, MD  more...
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Gastrointestinal (GI) symptoms typically develop about a week after the appearance of the characteristic rash, but may precede or accompany the onset of skin lesions in IgAV or occur weeks or months later. [71] The most common such symptom is colicky abdominal pain. In addition to abdominal pain, GI findings may include the following:

  • Nausea
  • Vomiting
  • Diarrhea with gross or occult blood
  • Hematemesis
  • Intussusception - This occurs in 2-3% of patients, and the lead point can be a submucosal hematoma
  • Bowel infarction, with or without perforation
  • Ileal stricture
  • Ileus with massive GI hemorrhage
  • Acute appendicitis [72, 73]

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