What environmental exposures may trigger the development of Henoch-Schönlein purpura (IgA vasculitis)?

Updated: Oct 28, 2020
  • Author: Rajendra Bhimma, MBChB, MD, PhD, DCH (SA), FCP(Paeds)(SA), MMed(Natal); Chief Editor: Craig B Langman, MD  more...
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Answer

Environmental exposure to the following may precede the development of IgAV:

  • Drugs (eg, ampicillin, erythromycin, penicillin, quinidine, quinine, losartan, and cytarabine [49] )
  • Foods
  • Horse serum
  • Cold exposure
  • Insect bites

Glomerulocystic kidney disease has also been noted.


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