Which individuals are at highest risk for Henoch-Schönlein purpura (IgA vasculitis)?

Updated: Jan 08, 2021
  • Author: Rajendra Bhimma, MBChB, MD, PhD, DCH (SA), FCP(Paeds)(SA), MMed(Natal); Chief Editor: Craig B Langman, MD  more...
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Answer

The prevalence of IgAV peaks in children aged 3-10 years, with the mean age at presentation being 6 years, but the condition is also seen in adults. [12]  It has been reported that IgAV will occur in 10-30 per 100,000 children younger than 17 years will develop IgAV. There is a strong ethnic influence on the incidence of the disease, with approximately 70 cases per 100,000 children annually in Asia. [13]  In the Northern Hemisphere, the disease occurs mostly between November and January. IgAV has typically been reported to be more common in males, with a male-to-female ratio ranging from 1.5-2:1, but some studies have found a more equal distribution between the sexes. [14, 15]


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