What are the signs and symptoms of Henoch-Schönlein purpura (IgA vasculitis)?

Updated: Jan 08, 2021
  • Author: Rajendra Bhimma, MBChB, MD, PhD, DCH (SA), FCP(Paeds)(SA), MMed(Natal); Chief Editor: Craig B Langman, MD  more...
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The typical prodrome of IgAV includes the following:

  • Headache
  • Anorexia
  • Fever

Subsequently, symptoms develop, of which the following are the most common:

  • Rash (95-100% of cases), especially involving the legs; this is the hallmark of the disease
  • Abdominal pain and vomiting (35-85%)
  • Joint pain (60-84%), especially involving the knees and ankles
  • Subcutaneous edema (20-50%)
  • Scrotal edema (2-35%)
  • Bloody stools

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