What are the possible adverse effects of albumin in the treatment of pediatric nephrotic syndrome?

Updated: Mar 04, 2020
  • Author: Jerome C Lane, MD; Chief Editor: Craig B Langman, MD  more...
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Answer

Infusion of 25% albumin can result in pulmonary edema, congestive heart failure, and acute kidney injury. Albumin should be used cautiously, sparingly, and only in those patients with hemoconcentration or diuretic-resistant edema. Slow infusion of 1 g/kg as a continuous infusion over 24 hours might help to limit complications.


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