What are the possible adverse effects of diuretics in the treatment of pediatric nephrotic syndrome?

Updated: Mar 04, 2020
  • Author: Jerome C Lane, MD; Chief Editor: Craig B Langman, MD  more...
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Answer

Loop diuretics (furosemide, bumetanide) commonly cause hypokalemia and contraction alkalosis. Serum electrolytes should be monitored and electrolyte abnormalities treated as indicated.

Metolazone may augment these adverse effects. The use of potassium-sparing diuretics (spironolactone, amiloride) may help to limit hypokalemia.


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