What is the role of zinc in the treatment of pediatric nephrotic syndrome?

Updated: Mar 04, 2020
  • Author: Jerome C Lane, MD; Chief Editor: Craig B Langman, MD  more...
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A study examined oral zinc supplementation (10 mg daily) in children with SSNS. [95] The authors found a trend in the reduction of relapse frequency and an increase in remission length. However, the study was underpowered to show statistical significance.

In a study of 60 children with SSNS, patients were randomized to receive zinc or placebo in addition to standard treatment for 6 months. Patients treated with zinc demonstrated a 43% reduction in relapses compared with those who received placebo. [96]

Further studies are needed before the routine use of zinc supplementation can be recommended.

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