What is the histologic staging of pediatric nephrotic syndrome?

Updated: Mar 04, 2020
  • Author: Jerome C Lane, MD; Chief Editor: Craig B Langman, MD  more...
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Various staging schemes are recognized for the different histologic lesions of INS. In general, when referring to kidney biopsy, the severity and chronicity of the disease is determined by the extent of tubulointerstitial fibrosis. The greater the extent of fibrosis, the greater the irreversibility of the disease and the poorer the prognosis, regardless of histologic subtype.

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