Which urine protein quantification findings are characteristic of pediatric nephrotic syndrome?

Updated: Mar 04, 2020
  • Author: Jerome C Lane, MD; Chief Editor: Craig B Langman, MD  more...
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Answer

A first-morning urine protein/creatinine ratio is more easily obtained than a 24-hour urine study, is possibly more reliable, and excludes orthostatic proteinuria. A urine protein/creatinine ratio of more than 2-3 mg/mg is consistent with nephrotic-range proteinuria.

A 24-hour urine protein level of more than 40 mg/m2/hr also defines nephrotic-range proteinuria.


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