What are the signs and symptoms of acute kidney failure (AKF) in pediatric nephrotic syndrome?

Updated: Mar 04, 2020
  • Author: Jerome C Lane, MD; Chief Editor: Craig B Langman, MD  more...
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Acute kidney failure (AKF) is a rare complication of idiopathic nephrotic syndrome. Fever, rash, arthralgia, and eosinophilia with a "bland" urinalysis (minimal cellular elements) in the presence of AKF are typical of acute interstitial nephritis. However, obvious clinical symptoms may be absent except for the AKF and unremarkable urinalysis. Gross hematuria, flank pain, and thrombocytopenia may be signs of renal vein thrombosis. Hemoconcentration in the patient with anasarca might indicate intravascular volume depletion.

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