What are the sexual predilections of hematuria?

Updated: Jan 03, 2019
  • Author: Sanjeev Gulati, MD, MBBS, DNB(Peds), DM, DNB(Neph), FIPN(Australia), FICN, FRCPC(Canada); Chief Editor: Craig B Langman, MD  more...
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Answer

Sex may predispose a child to specific diseases that manifest as hematuria. For example, the sex-linked form of Alport syndrome has a male preponderance, whereas lupus nephritis tend to be more common in adolescent girls.

A 2017 American College of Obstetricians and Gynecologists Committee Opinion on Asymptomatic Microscopic Hematuria in Women concluded that the patient’s sex should influence the differential diagnosis as asymptomatic microscopic hematuria in women is less likely to be associated with urinary tract malignancy than in men. The risk of urinary tract malignancy is ≤ 0.5% in low-risk, never-smoking women younger than 50 years of age without gross hematuria and with fewer than 25 red blood cells per high-power field. [3]


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