Which lab tests are performed in the workup of hematuria?

Updated: Jan 03, 2019
  • Author: Sanjeev Gulati, MD, MBBS, DNB(Peds), DM, DNB(Neph), FIPN(Australia), FICN, FRCPC(Canada); Chief Editor: Craig B Langman, MD  more...
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Answer

The laboratory tests ordered for the evaluation of hematuria must be based on the clinical history and the physical examination. Tests that may be helpful include the following:

  • Urinalysis with careful microscopic review of the urine sample

  • Phase-contrast microscopy to help determine the source of the bleeding. In clinical practice this is not always feasible.

  • Electrolytes, Blood urea nitrogen (BUN) and serum creatinine levels

  • Hematologic and coagulation studies (eg, complete blood count [CBC] and, sometimes, platelet counts)

  • Random Urine calcium and creatinine levels

  • Serologic testing (eg, complement, antistreptolysin [ASO], anti-DNase B, antinuclear antibody [ANA], and double-stranded DNA [dsDNA], ANCA)

  • Urine culture for suspected urinary tract infection (UTI)


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