What is acute poststreptococcal glomerulonephritis (APSGN)?

Updated: Dec 05, 2018
  • Author: Rajendra Bhimma, MBChB, MD, PhD, DCH (SA), FCP(Paeds)(SA), MMed(Natal); Chief Editor: Craig B Langman, MD  more...
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The term acute glomerulonephritis technically describes a pathological process not due to direct infection of the kidney but one characterized by inflammation and/or cellular proliferation of the glomerulus. The clinical presentation is of an acute nephritic syndrome with hematuria, proteinuria, and varying degrees of hypertension with our without evidence of volume overload.  Rarely the presentation may be of that of nephrotic syndrome (severe proteinuria, hypoalbuminemia and edema with accompanying hyperlipidemia) or rapidly progressive acute kidney injury.

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