Which medications in the drug class Volume Expanders are used in the treatment of Necrotizing Enterocolitis?

Updated: Dec 27, 2017
  • Author: Shelley C Springer, JD, MD, MSc, MBA, FAAP; Chief Editor: Muhammad Aslam, MD  more...
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Volume Expanders

Patients with severe illness may experience fluid shifts to the extracellular space, resulting in intravascular depletion that requires expansion.

Albumin (5% and 25%)

Albumin is used to increase intravascular oncotic pressure in hypovolemia and helps to mobilize fluids from the interstitial to the intravascular space. The concentration can be either 5% (5 g/100 mL) or 25% (25 g/100 mL), depending on the desired effect.

Sodium chloride hypertonic, ophthalmic (Normal saline, NS, Isotonic saline)

Sodium chloride can be used as a volume expander and can be as effective as albumin in acute hypovolemia.

Fresh frozen plasma

Fresh frozen plaza is especially helpful as a volume expander in patients with concomitant coagulopathy.

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