How can the risk and severity of necrotizing enterocolitis (NEC) be moderated?

Updated: Dec 27, 2017
  • Author: Shelley C Springer, JD, MD, MSc, MBA, FAAP; Chief Editor: Muhammad Aslam, MD  more...
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Answer

Experimental and meta-analytical evidence suggests that exogenous administration of the probiotics bifidobacteria and lactobacilli (nondigestible substances that selectively promote the growth of beneficial, probioticlike bacteria normally present in the gut) may moderate the risk and severity of NEC in preterm infants. [4, 39, 40, 41]

Placement of a peripheral arterial line may be helpful at the beginning of the patient's treatment to facilitate serial arterial blood sampling and invasive monitoring.

Placement of a central venous catheter for administration of pressors, fluids, antibiotics, and blood products is prudent because severely affected patients often have complications that include sepsis, shock, and disseminated intravascular coagulation (DIC).

If the baby is rapidly deteriorating, with apnea and/or signs of impending circulatory and respiratory collapse, airway control and initiation of mechanical ventilation is indicated.


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