Which medications in the drug class Synthetic surfactants are used in the treatment of Pulmonary Interstitial Emphysema?

Updated: Jun 25, 2019
  • Author: Abhay J Bhatt, MD, MBBS; Chief Editor: Muhammad Aslam, MD  more...
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Answer

Synthetic surfactants

Exosurf®, Lucinactant (Surfaxin®)

It is produced synthetically in laboratory.  Previous synthetic surfactant only contained phospholipids, with colfosceril palmitate (Exosurf®) the most commonly trialled protein-free synthetic surfactant The prime factor has been the development of protein-containing synthetic surfactant. It had been shown that its therapeutic effect was inferior to that of natural surfactant. The rise of protein-containing synthetic surfactant, such as lucinactant (Surfaxin®), has offered scientists a new avenue to further expand upon our advancement in surfactant as its action has been hypothesised to be as effective as, or even better than, natural surfactant.


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