What is the role of lab tests in the workup of pediatric omphalocele and gastroschisis (abdominal wall defects)?

Updated: Nov 05, 2019
  • Author: James G Glasser, MD, MA, FACS; Chief Editor: Dharmendra J Nimavat, MD, FAAP  more...
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Elevation of maternal serum alpha-fetoprotein (MSAFP) is associated with abdominal wall defects. MSAFP levels are higher in gastroschisis than in omphalocele, and they are also increased in spina bifida, which additionally increases the ratio of acetylcholinesterase and pseudocholinesterase. [6]

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