What is the prognosis of pediatric gastroschisis?

Updated: Nov 05, 2019
  • Author: James G Glasser, MD, MA, FACS; Chief Editor: Dharmendra J Nimavat, MD, FAAP  more...
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Answer

The prognosis of infants with gastroschisis depends upon the severity of associated problems, such as prematurity, intestinal atresia and dysfunction, and possibly short gut. A population-based cohort study from 28 pediatric surgical centers in the United Kingdom and Ireland analyzed the 1-year outcomes of infants with gastroschisis and found that infants with complex gastroschisis required longer hospital stays and had more complications than infants with simple gastroschisis. [18] Classifying infants with gastroschisis into "simple" versus "complex" (macroscopic intestinal abnormalities) may be a reliable predictor of outcome. [18] A separate population-based study of 502 Australian infants with abdominal wall defects (166 omphalocele, 336 gastroschisis) reported similar findings of longer hospital stays and parenteral nutrition as well as higher rates of infection but lower overall mortality in infants with gastroschisis compared to those with omphalocele. [19]

The prognosis has been greatly improved by antenatal sonography, which allows identification of infants with abdominal wall defects and referral to tertiary centers where prenatal, obstetrical, and pediatric surgical expertise is available. [15, 16, 20]


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