What is the global prevalence of pediatric omphalocele and gastroschisis (abdominal wall defects)?

Updated: Nov 05, 2019
  • Author: James G Glasser, MD, MA, FACS; Chief Editor: Dharmendra J Nimavat, MD, FAAP  more...
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Answer

The combined incidence of omphalocele and gastroschisis is 1 case per 3,500 births. Epidemiologic data compiled over the last four to five decades show that the incidence of omphalocele has remained constant, whereas that of gastroschisis has increased three- to four-fold. See the table below.

Table 1. Incidence Rates for Gastroschisis and/or Omphaloceles in Various Regions and Time Periods. [1, 15, 16, 17] (Open Table in a new window)

Country

Time Period / Incidence

Time Period / Incidence

Japan

1975-1980

1996-1997

Gastroschisis

1/77,000

1/20,000

Omphalocele

1/30,000

1/27,000

 

 

 

England and Wales

1987

1991

Gastroschisis

1/10,000

2/10,000

Omphalocele

1/10,000

1/12,500

 

 

 

Galveston, Texas

1983

2002

Gastroschisis

1/4000

1/900

 

 

 

England and Wales

1995

2005

Gastroschisis

1/7500

1/2500


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