What is the prevalence of pediatric omphalocele and gastroschisis (abdominal wall defects)?

Updated: Nov 05, 2019
  • Author: James G Glasser, MD, MA, FACS; Chief Editor: Dharmendra J Nimavat, MD, FAAP  more...
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Analysis of 2012-2016 data from 30 US population-based birth defect surveillance programs by the National Birth Defects Prevention Network (NBDPN) focused on abdominal wall defects, specifically gastroschisis and omphalocele. It found an overall prevalence of 4.3 per 10,000 live births for gastroschisis and 2.1 per 10,000 live births for omphalocele. [10] Gastroschisis was more frequent among mothers younger than 25 years and more likely to occur when mothers had low or normal prepregnancy weights; it was half as likely as omphalocele to occur in conjunction with other birth defects. Omphalocele was more common in mothers older than 40 years, more likely to occur in overweight/obese mothers, and twice as likely as gastroschisis to concomitantly occur with other birth defects. [10]

Allman et al evaluated retrospective discharge data (1997-2015) for the prevalence of infants with gastroschisis in US neonatal intensive care units (NICUs). Of 1,158,755 total discharges, 6,023 infants (5.2 per 1000 discharges) had gastroschisis and 1,885 (1.6 per 1000 discharges) had an omphalocele. [14] The rate of gastroschisis increased from 2.9 to 6.4 per 1000 discharges over a 12-year period (1997-2008), gradually declined over the next 4 years (2008-2011) from 6.4 to 4.7 per 1000 discharges, and then remained stable thereafter. The rate of omphalocele was stable over the same time periods, at 1-2 per 1000 discharges. [14]

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