What is the role of epidermal growth factor (EGF) levels in the pathophysiology of breast milk jaundice?

Updated: Dec 07, 2017
  • Author: Prashant G Deshpande, MD; Chief Editor: Muhammad Aslam, MD  more...
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Answer

Epidermal growth factor (EGF) is responsible for growth, proliferation, and maturation of the gastrointestinal tract in newborns, and it is vital for adaptation after birth. Higher EGF serum and breast milk levels have been noted in patients with breast milk jaundice. [9]  Reduced gastrointestinal motility and increased bilirubin absorption and uptake are thought to be the mechanisms.


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