When is transfer to a tertiary NICU indicated in the treatment of hypoxic-ischemic encephalopathy (HIE)?

Updated: Jul 18, 2018
  • Author: Santina A Zanelli, MD; Chief Editor: Dharmendra J Nimavat, MD, FAAP  more...
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Infants who present in a level I or II center may require transfer to a tertiary neonatal intensive care unit (NICU) for definitive neurodiagnostic studies (electroencephalography [EEG] and neuroimaging), consultation with a pediatric neurologist, and evaluation for therapeutic hypothermia. Based on the current recommendations, therapeutic hypothermia must be initiated within 6 hours after birth. [127] Timely referral is essential to provide therapeutic hypothermia. If that window (of 6 hours) has passed, infants will still benefit from the expertise of level III and higher centers.

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