What are the signs and symptoms of moderately severe hypoxic-ischemic encephalopathy (HIE)?

Updated: Jul 18, 2018
  • Author: Santina A Zanelli, MD; Chief Editor: Dharmendra J Nimavat, MD, FAAP  more...
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Moderately severe hypoxic-ischemic encephalopathy

  • The infant is lethargic, with significant hypotonia and diminished deep tendon reflexes

  • The grasping, Moro, and sucking reflexes may be sluggish or absent

  • The infant may experience occasional periods of apnea

  • Seizures typically occur early within the first 24 hours after birth

  • Full recovery within 1-2 weeks is possible and is associated with a better long-term outcome

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