Which variables of neonatal management influence survival after initial stabilization in maternal chorioamnionitis?

Updated: May 08, 2018
  • Author: Fayez M Bany-Mohammed, MD; Chief Editor: Ted Rosenkrantz, MD  more...
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After initial stabilization of a neonate with potential infection in the delivery room, attention is directed toward the following variables that influence survival:

  • Warmth, monitoring of vital signs, maintenance of fluid and electrolyte balance, and correction of significant metabolic acidosis
  • Management of the circulation, including correction of hypovolemia, and enhancement of cardiac performance with inotropic drugs if sepsis-related myocardial dysfunction is noted
  • Glucose homeostasis
  • Treatment of respiratory distress that may entail surfactant replacement (for pneumonia, respiratory distress syndrome) and different modes of assisted ventilation (Inhaled nitric oxide may be considered as a therapy in the presence of pulmonary hypertension.)
  • Assessment and treatment of thrombocytopenia and coagulopathy, if present

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