What is the management approach to sepsis in neonates associated with maternal chorioamnionitis?

Updated: May 08, 2018
  • Author: Fayez M Bany-Mohammed, MD; Chief Editor: Ted Rosenkrantz, MD  more...
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An extensive discussion of the management of septic neonates is not possible in this article, but it is available in other Medscape Drugs and Diseases chapters (see Neonatal Sepsis). Critical points to ensure intact survival of the neonate are mentioned for completeness. For example, ventilator management and surfactant replacement therapy can be used to treat the neonate with congenital bacterial pneumonia, but a complete discussion of the techniques involved in this therapy are covered in other articles. Physicians and nurses attending the delivery of a newborn whose mother is suspected of having chorioamnionitis should be ready to perform a full resuscitation, including intubation; providing positive-pressure ventilation; and treatment of hypovolemia, shock, and respiratory and/or metabolic acidosis. Low Apgar scores may be another indicator of sepsis.

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