Which conditions resemble neonatal sepsis associated with chorioamnionitis?

Updated: May 08, 2018
  • Author: Fayez M Bany-Mohammed, MD; Chief Editor: Ted Rosenkrantz, MD  more...
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Because one physiologic system may affect another, signs and symptoms may originate from more than one dysfunctional organ. However, many neonatal conditions resemble neonatal sepsis; thus, physician caregivers must have an open mind regarding other clinical conditions that may involve signs and symptoms resembling those of neonatal sepsis. Those conditions include, but are not limited to, the following:

  • Cardiovascular malformations, especially left-sided obstructive lesions causing poor systemic cardiac output
  • Endocrine disorders that may also cause shocklike states, such as different types of congenital adrenal insufficiency or hypoglycemia associated with hyperinsulinemia
  • Serious CNS trauma or dysfunction from any cause and subtle seizures with systemic manifestations
  • Anemia caused by unrecognized isoimmunization or blood loss from conditions such as fetomaternal transfusion syndrome

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