What are the clinical signs and symptoms of chorioamnionitis?

Updated: May 08, 2018
  • Author: Fayez M Bany-Mohammed, MD; Chief Editor: Ted Rosenkrantz, MD  more...
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Answer

The time-honored clinical signs and symptoms of chorioamnionitis include the following:

  • Intrapartum fever: The National Institute of Child Health and Human Development (NICHD) workshop report defined maternal fever as temperature of at least 39.0°C [102.2°F] or 38.0°C [100.4°F] to 38.9°C [102.02°F] on two occasions 30 minutes apart, [1] without another clear source. [2]
  • Significant maternal tachycardia (>120 beats per minute [bpm])
  • Base line fetal tachycardia (>160 bpm for 10 min or longer, excluding accelerations, decelerations, and periods of marked variability)
  • Maternal leukocytosis (total blood leukocyte count >15,000 cells/μL) in the absence of corticosteroids
  • Purulent-appearing fluid coming from the cervical os, as visualized by speculum examination
  • Other nonspecific signs such as maternal tachycardia and uterine tenderness are deemphasized by the NICHD. [2]

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