What are the demographics of chorioamnionitis?

Updated: May 08, 2018
  • Author: Fayez M Bany-Mohammed, MD; Chief Editor: Ted Rosenkrantz, MD  more...
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In select populations, race may increase the risk of maternal chorioamnionitis and preterm delivery. [84] Studying histologic chorioamnionitis and preterm birth, Holzman et al observed evidence of inflammatory pathology in 12% of placentas from white women and women of other races compared to 55% in black women. [85]  However, it is difficult to separate race form other hostile environmental circumstances (eg, violence, inadequate prenatal care, malnutrition) that could lead to chorioamnionitis and adverse maternal and neonatal outcomes.

Existing data on the role of sex in EOS are conflicting. Although some researchers identified male sex as a risk factor for EOS, [17] others failed to demonstrate this association. [86, 21] Advanced maternal age alone, defined as being older than 35 years, has not been identified as a risk factor for chorioamnionitis. However, teenage pregnancy raises the risk of chorioamnionitis. [87, 88, 89]

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