How is scrub typhus prevented?

Updated: Apr 19, 2018
  • Author: David J Cennimo, MD, FAAP, FACP, FIDSA, AAHIVS; Chief Editor: Russell W Steele, MD  more...
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Preventive measures in endemic areas include the use of protective clothing and insect repellents (potentially including plant essential oils [69] ). Short-term vector reduction using environmental insecticides and vegetation control can be instituted.

Chemoprophylaxis regimens have included the following:

  • A single dose of doxycycline given weekly, started before exposure and continued for 6 weeks after exposure [1]

  • A single oral dose of chloramphenicol or tetracycline given every 5 days for a total of 35 days, with 5-day nontreatment intervals

Reports of scrub typhus outbreaks in endemic areas and decreased effectiveness of antibiotic treatment suggest a continued need for a suitable vaccine. [70] At present, no such vaccine is available. [71]

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