Which lab tests may be indicated to diagnose Pseudomonas infections in specific sites?

Updated: Dec 17, 2018
  • Author: Selina SP Chen, MD, MPH; Chief Editor: Russell W Steele, MD  more...
  • Print
Answer

The following additional studies may be indicated, depending on the site of infection:

  • Culture of the purulent discharge helps diagnose suppurative otitis media or malignant otitis externa.

  • Corneal scrapings and culture may reveal pseudomonal involvement.

  • Culture of vegetations from patients with pseudomonal infectious endocarditis (IE) reveals high quantities of the organisms, although diagnosis is usually confirmed by a repeated blood culture.

  • Sputum Gram stain and culture may be indicated to evaluate for respiratory infection. This is especially recommended in children who may be predisposed to such infections.

  • Blood gas levels may reveal hypoxemia, with or without hypercarbia.

  • Wound and burn cultures can be helpful to identify pseudomonal infections.

  • Urinalysis with culture and sensitivity is helpful when evaluating for urinary tract infection (UTI). Although rare, sloughing of vesical membrane in the urine can indicate complications of pseudomonal infections.

  • Obtain stool cultures in patients with diarrhea. Note, however, that pseudomonal organisms produce no toxins.

Diagnosis of glanders can be confirmed by isolating B mallei from blood, sputum, urine, or skin lesions. No serologic tests are available. Diagnosis of melioidosis can be confirmed by isolating B pseudomallei from the blood, urine, sputum, or skin lesions. Detecting antibodies to the bacteria in the blood is another method.


Did this answer your question?
Additional feedback? (Optional)
Thank you for your feedback!